Damage to the spinal discs over time or from sudden strain is one of the most common causes of back and neck pain. Excessive pressure or herniation of the discs can press on nerve roots, leading to pain and restricted movement. Today, many methods have been developed to alleviate this problem.
Definition | – A minimally invasive method used to treat pain from disc herniation (lumbar or cervical). Ozone gas, radiofrequency energy, or laser energy is used to reduce pressure inside the disc. |
Indications | – Mild to moderate disc herniation – Back, neck, or leg/arm pain (radicular) due to nerve root compression – Patients unresponsive to conservative treatments (medications, physical therapy) |
Procedure | – Performed under local anesthesia. – A needle‑like device is placed into the disc under fluoroscopic guidance. – Ozone gas, radiofrequency, or laser energy is delivered through the device tip to vaporize nucleus pulposus tissue. – Disc pressure decreases and nerve compression is relieved. |
Advantages | – Minimally invasive – No general anesthesia required – Rapid recovery time – Lower risk compared to open surgery – No pain felt during the procedure |
Risks & Complications | – Mild pain or discomfort post‑procedure – Infection (rare) – Nerve injury (very rare) – Disc damage or inadequate treatment during the procedure |
Success Rate | – 70–80% pain reduction in appropriately selected patients. – Not indicated if disc height is less than half normal or if severe annular calcification is present. |
Preparation | – Patient should inform the doctor of all medications (especially anticoagulants). – Fasting may be required before the procedure. – MRI and other imaging results should be reviewed. |
Duration | – Typically 30 minutes. |
Recovery | – Patients are usually discharged about 2 hours afterward. – Return to daily activities in 1–2 days. – Avoid heavy lifting and strenuous activities for a time. |
Alternatives | – Micro‑discectomy – Endoscopic discectomy – Epidural steroid injections – Conservative treatments (physical therapy, medications) |


Prof. Dr. Özgür KILIÇKESMEZ
Interventional Radiology / Interventional Neuroradiology
What Is Nucleoplasty and What Role Do Spinal Discs Play?
The spine is cushioned by discs between each vertebra. Each disc’s center, the nucleus pulposus, is soft and gel‑like, while the outer ring, the annulus fibrosus, is tougher and fibrous. Discs prevent vertebrae from rubbing and support body movement and flexibility.
Over time or from sudden trauma, the gel‑like nucleus can bulge or herniate outward, pressing on nerve roots and causing pain or numbness. Nucleoplasty is a minimally invasive treatment for patients whose annulus fibrosus remains intact (contained herniation).
Imagine an overfilled jam cookie whose filling is pressing out at the edges—by removing some filling, you relieve that pressure. In nucleoplasty, the “filling” is the nucleus pulposus, and the “cookie edge” is the annulus fibrosus.
Which Patients Are Good Candidates for Nucleoplasty?
- Herniation Size & Type: Best for contained herniations where the annulus is not fully torn. Large or sequestered herniations have lower success rates.
- Chronic or Radicular Pain: Persistent back/neck pain radiating to the leg or arm, unresponsive to conservative measures.
- Overall Health: Not suitable for severe spinal instability, stenosis, or spondylolisthesis; bleeding disorders or active infection must be ruled out.
- Imaging: MRI or CT must clearly show the herniation’s location, size, and nerve root compression.
How Does Nucleoplasty Reduce Pain?
When a disc herniates, its internal pressure rises, mechanically compressing nerves and releasing inflammatory mediators. In nucleoplasty, a small probe delivers radiofrequency or laser energy to vaporize part of the nucleus pulposus (or ozone to shrink it), thereby:
- Reducing pressure: Less mechanical load on the nerve root.
- Lowering inflammation: Less chemical irritation inside the disc.
Think of withdrawing a bit of excess filling from a jam jar so the lid can close without pressure—that’s the principle behind nucleoplasty.
Procedure Steps
- Preparation: Review history, imaging; adjust anticoagulants if needed; local anesthesia or sedation.
- Positioning: Patient prone (for lumbar) or appropriate neck position; fluoroscopy to target the level.
- Needle Placement: Trocar advanced into the disc under live imaging.
- Energy Delivery: A fine catheter delivers RF or laser energy to create micro‑channels; duration ~30 min per level.
- Closure: Catheter removed; small dressing applied—no major incision.
Advantages of Nucleoplasty
- Less tissue damage: No large muscle or ligament incisions.
- Less postoperative pain: Typically mild and managed with simple analgesics.
- Rapid recovery: Many resume normal activities the next day.
- Short hospital stay: Often same‑day discharge.
Recovery Timeline
- Immediate: Few hours of observation.
- Home rest: Light activities for 1–2 days; avoid heavy lifting.
- Physical therapy: Strengthening and stretching exercises.
- Follow‑up: Weeks to months to monitor pain relief and disc status.
- Return to work: Many desk jobs in one week; heavy labor later.
Risks & Complications
- Infection (discitis): Rare with sterile technique.
- Nerve injury: Very rare but possible during needle passage.
- Temporary pain or numbness: Usually self‑limited.
- Insufficient relief: Variable success based on patient factors.
- Re‑herniation: Possible with future strain or trauma.
Nucleoplasty vs. Traditional Disc Surgery
- Access: Nucleoplasty via needle vs. microdiscectomy via small incision.
- Recovery: Faster with nucleoplasty; surgery requires longer healing.
- Pain & complications: Lower with nucleoplasty.
- Indications: Nucleoplasty for contained herniations; surgery for large or sequestered herniations.
Long‑Term Considerations
- Activity: Avoid heavy lifting; low‑impact exercise recommended.
- Physical therapy: Strengthen core and postural muscles.
- Weight control: Reduces spinal load.
- Ergonomics: Proper desk setup and posture breaks.
- Routine check‑ups: MRI at ~3 months; annual clinical reviews.
Durability of Results
With proper patient selection, many experience sustained relief at 12 months and beyond. However, recurrence can occur at the same or different disc levels, depending on lifestyle and spinal health.
Pre‑Procedure Preparation
- Confirm diagnosis: MRI to verify disc herniation.
- Adjust medications: Manage anticoagulants per physician guidance.
- Fasting: Typically not required for local anesthesia; brief fasting if sedated.
- Comfortable attire: Loose clothing for same‑day discharge.
How to Minimize Complications After Nucleoplasty?
- Sterile Conditions: Perform the procedure in a fully sterile environment to reduce infection risk.
- Proper Technique: Use fluoroscopy (live X‑ray) or other imaging to ensure accurate targeting of the correct disc level.
- Patient Education: After the procedure, avoid heavy lifting and improper lifting techniques for a prescribed period.
- Adherence to Follow‑ups: Attend scheduled postoperative visits to monitor the healing process.
How to Enhance Long‑Term Success of Nucleoplasty?
- Regular Exercise Routines: Engage in spine‑friendly programs like yoga or Pilates, avoiding overly strenuous movements.
- Posture Training: Learn correct techniques for sitting, standing, and bending to prevent excessive disc loading.
- Weight Management: Maintain a healthy weight to reduce stress on the discs.
- Avoid Sudden, Strenuous Movements: Newly healed discs can be compromised by sudden heavy lifting or high‑stress activities.
- Regular Medical Check‑ups: Long‑term follow‑up allows early detection of small changes or recurring symptoms.
Is Nucleoplasty Safe and Effective?
- Safety: Studies to date show a low rate of serious complications with nucleoplasty.
- Effectiveness: With proper patient selection and technique, it yields successful outcomes for disc‑related back and neck pain.
- Rapid Recovery: Faster convalescence compared to traditional surgery, allowing earlier return to daily life.
- Long‑Term Results: When combined with lifestyle modifications, durable benefits are achievable.
Nucleoplasty stands out as a less invasive alternative for contained, moderate‑sized herniations causing pain, compared to open surgery. However, it may not be suitable for all patients—large herniations, severe nerve compression, or additional spinal pathology may require other treatments.
It is an option for patients whose back or neck pain from disc herniation has not responded to medical therapy or physical therapy, offering a short recovery period. As with any intervention, comprehensive evaluation and individualized risk‑benefit analysis are essential. When performed under appropriate conditions, the majority of patients experience significant pain relief and improved quality of life.
Individuals with back or neck pain and suspected disc herniation should undergo thorough examination and imaging studies to clarify their condition, and discuss nucleoplasty and other treatment options with their physician.
Frequently Asked Questions
Although rest is recommended for the first few days after the procedure, most patients can resume social activities quickly. Light walks or low‑intensity activities are usually tolerated within about a week. However, you should follow your doctor’s guidance before returning to more active hobbies like dancing or fitness to prevent long‑term issues. Rushing the process is not advisable.
No, the procedure generally does not impede your weight loss efforts. It’s important to gradually increase exercises that reduce load on your lower back. Your doctor may recommend starting with light walks or low‑impact sports. You should also maintain a balanced diet to support metabolic health. Unless you require additional surgery or experience trauma, you do not need to postpone your weight loss goals.
There is no strict seasonal restriction, but extreme heat or cold during recovery can affect your comfort. Risky conditions like icy roads increase the chance of falls and sudden strain early on. In hot weather, sweating and overheating can also be problematic. Plan the timing with your doctor based on local climate to optimize healing conditions.
Since there is no large incision, most people can resume light activities the next day. However, avoid heavy lifting and strenuous physical activity for several weeks. Recovery times vary between individuals.
Extended sitting can cause discomfort in your lower back. You may take short flights as early as the day after the procedure. Choose an aisle seat and get up to walk periodically to promote circulation. When planning travel, consult your doctor to avoid critical phases of your recovery. Avoid scheduling travel on the same day as the procedure.
A mattress that is comfortable yet supportive of your spine’s natural curvature helps maintain alignment. Very firm mattresses can put extra pressure on your back, while very soft ones may fail to support proper posture. Orthopedic models of medium firmness are generally recommended, though personal preference also matters. If you plan to change your mattress, do so with your doctor’s approval during the first few weeks.
Nucleoplasty can provide long‑lasting relief when indicated properly. However, similar issues may recur at the same level or adjacent segments over time. Initially, conservative measures like physical therapy and medications are attempted again. If those fail and clinical evaluation confirms disc‑related symptoms, a repeat procedure may be considered. Decisions are based on patient age, overall health, and the success of the previous procedure.
Because local anesthesia is used, patients generally do not experience severe pain. You may feel mild pressure or discomfort, which is usually well tolerated. Sedation can be added if desired.
Avoid long‑distance travel for the first week if possible. If flying or taking a bus, plan frequent walks to break up sitting. When traveling by car, take regular breaks to stretch. Ask for help lifting luggage or heavy items. If you need pain medication during travel, discuss suitable options and dosages with your doctor in advance.
Physical therapy is generally advised—no sooner than one week post‑procedure—to boost treatment success and reduce recurrence risk. Exercises that strengthen the muscles around the spine aid healing. The duration and intensity depend on the patient’s clinical status.
Plan your return to sports gradually. Begin by strengthening the supporting muscles around your spine with low‑impact activities like walking or stationary cycling. Avoid heavy lifting, and slowly increase training intensity. Emphasize stretching to relax tight muscle groups. If you are a competitive athlete, work with your coach and physician to develop a tailored program. Always listen to your body—stop or modify any exercise that causes pain or discomfort.
There is no universal recommendation for bracing. Some physicians may suggest short‑term brace use for comfort, but prolonged use is generally not advised. Decisions are made based on each patient’s spinal condition.
In addition to medications, hot or cold therapy can help control pain. Some patients find acupuncture or dry needling beneficial. Meditation and breathing exercises can reduce tension and modulate pain perception. Transcutaneous electrical nerve stimulation (TENS) may also offer temporary relief. Always use these methods under your physician’s guidance.
Chronic back or neck pain can affect mood and routine. Before deciding on nucleoplasty, clarify your expectations and concerns. Speaking with a psychologist or counselor can help reduce anxiety and uncertainty. Support from family and friends boosts motivation. Practice breathing exercises or light meditation to calm your mind before the procedure.
Yes—reviewing your diet can support healing. A protein‑ and fiber‑rich diet promotes tissue repair and prevents constipation, which can strain your back. Staying well‑hydrated accelerates cell metabolism and reduces inflammation. Anti‑inflammatory foods rich in omega‑3s are also beneficial. Limit sugar and processed foods to help with weight management.
Most patients can drive short distances within the first week. For long trips or stop‑and‑go traffic, follow your doctor’s advice to avoid placing extra stress on your spine.
Avoid deep or vigorous massage over the needle entry site until it has fully healed. Light massage or skincare is typically safe after a few weeks, but apply only gentle pressure. Avoid deep tissue or sports massage until cleared by your doctor. For skincare, wait until after your first follow‑up to minimize infection risk.
Smoking impairs circulation and reduces oxygen delivery to tissues, slowing healing in your discs and surrounding structures. Tobacco also increases inflammation and complicates pain management. Reducing or quitting smoking after nucleoplasty promotes faster recovery and lowers complication risk.

Prof. Dr. Özgür Kılıçkesmez graduated from Cerrahpaşa Medical Faculty in 1997. He completed his specialization at Istanbul Education and Research Hospital. He received training in interventional radiology and oncology in London. He founded the interventional radiology department at Istanbul Çam and Sakura City Hospital and became a professor in 2020. He holds many international awards and certificates, has over 150 scientific publications, and has been cited more than 1500 times. He is currently working at Medicana Ataköy Hospital.
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