{"id":9676,"date":"2024-10-09T10:36:39","date_gmt":"2024-10-09T07:36:39","guid":{"rendered":"https:\/\/ozgurkilickesmez.com\/?p=9676"},"modified":"2025-09-04T21:03:49","modified_gmt":"2025-09-04T18:03:49","slug":"ire-nanoknife-in-cancerul-de-prostata","status":"publish","type":"post","link":"https:\/\/ozgurkilickesmez.com\/ro\/ire-nanoknife-in-cancerul-de-prostata\/","title":{"rendered":"IRE (NanoKnife) \u00een cancerul de prostat\u0103"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">IRE Nanoknife \u00een cancerul de prostat\u0103 este o tehnic\u0103 avansat\u0103 de abla\u021bie care utilizeaz\u0103 impulsuri electrice pentru a distruge celulele tumorale. Procedura se bazeaz\u0103 pe electroporarea ireversibil\u0103, p\u0103str\u00e2nd structurile vasculare \u0219i nervoase adiacente intacte.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Tratamentul cu Nanoknife se efectueaz\u0103 sub ghidaj imagistic \u0219i permite distrugerea precis\u0103 a leziunii tumorale. Avantajul metodei const\u0103 \u00een men\u021binerea func\u021bionalit\u0103\u021bii prostatei \u0219i reducerea riscurilor asociate interven\u021biilor radicale.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">O particularitate a IRE este absen\u021ba efectului termic, ceea ce o diferen\u021biaz\u0103 de alte metode ablative precum radiofrecven\u021ba sau HIFU. Astfel, riscul de afectare a \u021besuturilor din jur este semnificativ redus.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">IRE Nanoknife este recomandat\u0103 pacien\u021bilor cu cancer de prostat\u0103 localizat, care caut\u0103 o alternativ\u0103 minim invaziv\u0103. Procedura ofer\u0103 control oncologic eficient \u0219i o calitate a vie\u021bii superioar\u0103 pe termen lung.<\/span><\/p>\n<table>\n<tbody>\n<tr>\n<td>Metod\u0103 de tratament<\/td>\n<td>Electroporare Irreversibil\u0103 (IRE) &#8211; NanoKnife<\/td>\n<\/tr>\n<tr>\n<td>Defini\u021bie<\/td>\n<td>\u00cen cancerul de prostat\u0103, se utilizeaz\u0103 impulsuri de \u00eenalt\u0103 tensiune pentru a cre\u0219te permeabilitatea membranei celulelor canceroase, determin\u00e2nd moartea acestora, printr-o procedur\u0103 minim invaziv\u0103.<\/td>\n<\/tr>\n<tr>\n<td>Zone de utilizare<\/td>\n<td>Cancer de prostat\u0103 \u00een stadiu incipient, tumori mici \u0219i localizate, pacien\u021bi care nu pot fi supu\u0219i interven\u021biei chirurgicale sau radioterapiei ori care nu doresc aceste tratamente.<\/td>\n<\/tr>\n<tr>\n<td>Avantaje<\/td>\n<td>Afecteaz\u0103 minimal nervii, vasele de s\u00e2nge \u0219i alte \u021besuturi din jur, fiind eficient \u00een zona tumoral\u0103 vizat\u0103; ajut\u0103 la conservarea func\u021biei urinare \u0219i sexuale.<\/td>\n<\/tr>\n<tr>\n<td>Proces de aplicare<\/td>\n<td>Sub anestezie general\u0103, se introduc electrozi sub ghidaj ecografic sau RMN \u00een zona tumoral\u0103; prin ace\u0219ti electrozi se aplic\u0103 impulsuri electrice asupra celulelor canceroase. Procedura dureaz\u0103, \u00een general, 1-2 ore.<\/td>\n<\/tr>\n<tr>\n<td>Efecte secundare<\/td>\n<td>Durere temporar\u0103 dup\u0103 procedur\u0103, risc de infec\u021bie a tractului urinar, rar dificult\u0103\u021bi la urinare, sensibilitate \u00een zona tratat\u0103; efectele secundare severe sunt rare.<\/td>\n<\/tr>\n<tr>\n<td>Rata de succes<\/td>\n<td>Are o rat\u0103 ridicat\u0103 de succes \u00een cazul tumorilor aflate \u00een stadiu incipient \u0219i localizate; eficien\u021ba difer\u0103 \u00een func\u021bie de m\u0103rimea \u0219i localizarea tumorii.<\/td>\n<\/tr>\n<tr>\n<td>Monitorizare \u0219i urm\u0103rire<\/td>\n<td>Dup\u0103 procedur\u0103, se verific\u0103 periodic nivelurile antigenului prostatic specific (PSA), iar reac\u021bia la tratament se evalueaz\u0103 prin RMN sau biopsie.<\/td>\n<\/tr>\n<tr>\n<td>Metode alternative<\/td>\n<td>Prostatectomie radical\u0103, radioterapie, metode de abla\u021bie focal\u0103 (crio-terapie, HIFU &#8211; ultrasunete focalizate de intensitate \u00eenalt\u0103).<\/td>\n<\/tr>\n<tr>\n<td>Afec\u021biuni asociate<\/td>\n<td>Cancer de prostat\u0103, tumori localizate cu risc sc\u0103zut \u0219i moderat.<\/td>\n<\/tr>\n<tr>\n<td>Profilaxie \u0219i preg\u0103tire<\/td>\n<td>Se recomand\u0103 administrarea de antibiotice \u00eenainte de procedur\u0103 pentru a reduce riscul de infec\u021bie; valorile PSA \u0219i rezultatele RMN sunt analizate \u00eenainte de procedur\u0103.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span data-sheets-root=\"1\">\n\t<section class=\"section\" id=\"section_267417686\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n\n<div class=\"row\"  id=\"row-1751038366\">\n\n\n\t<div id=\"col-638317656\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\" style=\"background-color:#1c58ef;\" >\n\t\t\t\n\t\t\t\n\n<div class=\"row\"  id=\"row-1746347042\">\n\n\n\t<div id=\"col-1875367181\" 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Interven\u021bional\u0103<\/em><\/span><\/p>\n\t\t\n<style>\n#text-4281218390 {\n  font-size: 1.25rem;\n}\n@media (min-width:550px) {\n  #text-4281218390 {\n    font-size: 2rem;\n  }\n}\n<\/style>\n\t<\/div>\n\t\n<p>Prof. Dr. K\u0131l\u0131\u00e7kesmez de\u021bine Certificatul de Competen\u021b\u0103 \u00een Radiologie din Turcia, Certificatul de Competen\u021b\u0103 \u00een Radiologie Interven\u021bional\u0103 din Turcia, Certificarea pentru tratamentul accidentului vascular cerebral \u0219i Certificatul European de Radiologie Interven\u021bional\u0103 (EBIR). \u00cen cariera sa academic\u0103, a c\u00e2\u0219tigat Premiul I Siemens pentru Radiologie \u00een 2008.<\/p>\n\n<a href=\"https:\/\/ozgurkilickesmez.com\/kimdir\/\" class=\"button white lowercase hide-for-small\" style=\"border-radius:15px;\">\n\t\t<span>CV<\/span>\n\t<\/a>\n\n\n<a href=\"https:\/\/ozgurkilickesmez.com\/kimdir\/oduller\/\" class=\"button white lowercase hide-for-small\" 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30px;\n  border-radius: 20px;\n}\n<\/style>\n\t<\/div>\n\n\t\n\n<\/div>\n\n\t\t<\/div>\n\n\t\t\n<style>\n#section_267417686 {\n  padding-top: 30px;\n  padding-bottom: 30px;\n}\n<\/style>\n\t<\/section>\n\t<\/span><\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_89 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Con\u021binutul articolului<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #ffffff;color:#ffffff\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 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func\u021bioneaz\u0103 NanoKnife?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/ozgurkilickesmez.com\/ro\/ire-nanoknife-in-cancerul-de-prostata\/#Cine_este_candidat_pentru_NanoKnife_in_tratamentul_cancerului_de_prostata\" >Cine este candidat pentru NanoKnife \u00een tratamentul cancerului de prostat\u0103?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/ozgurkilickesmez.com\/ro\/ire-nanoknife-in-cancerul-de-prostata\/#Cat_de_eficient_este_NanoKnife_in_tratarea_cancerului_de_prostata\" >C\u00e2t de eficient este NanoKnife \u00een tratarea cancerului de prostat\u0103?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/ozgurkilickesmez.com\/ro\/ire-nanoknife-in-cancerul-de-prostata\/#Care_este_perspectiva_pe_termen_lung_pentru_pacientii_tratati_cu_NanoKnife\" >Care este perspectiva pe termen lung pentru pacien\u021bii trata\u021bi cu NanoKnife?<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Ce_este_Electroporarea_Irreversibila_IRE_si_cum_functioneaza_NanoKnife\"><\/span>Ce este Electroporarea Irreversibil\u0103 (IRE) \u0219i cum func\u021bioneaz\u0103 NanoKnife?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Electroporarea Irreversibil\u0103 (IRE), denumit\u0103 \u0219i NanoKnife, este o metod\u0103 minim invaziv\u0103 folosit\u0103 \u00een cancerul de prostat\u0103 \u0219i se bazeaz\u0103 pe o tehnic\u0103 de abla\u021bie non-termic\u0103. Aceast\u0103 tehnic\u0103 folose\u0219te impulsuri electrice de \u00eenalt\u0103 tensiune pentru a distruge structura membranei celulelor canceroase \u0219i a provoca pierderea homeostaziei celulare. Avantajul principal al IRE const\u0103 \u00een protejarea \u021besuturilor s\u0103n\u0103toase, permi\u021b\u00e2nd tratamentul sigur al zonelor unde se g\u0103sesc structuri sensibile, precum nervii \u0219i vasele de s\u00e2nge.<\/p>\n<p>Dispozitivul NanoKnife transmite impulsuri electrice direct c\u0103tre regiunea tumoral\u0103 prin intermediul electrozilor amplasa\u021bi \u00een jurul tumorii. Aceste impulsuri deterioreaz\u0103 ireversibil membranele celulare, declan\u0219\u00e2nd apoptoza. Astfel, riscul inflama\u021biei sau al leziunilor pentru \u021besuturile din jur scade.<\/p>\n<ul>\n<li><strong>Diferen\u021ba fa\u021b\u0103 de crioterapie:<\/strong> IRE distruge celulele canceroase prin impulsuri electrice, nu prin r\u0103cire. Crioterapia r\u0103ce\u0219te tumora, dar fluxul sangvin poate \u00eempiedica sc\u0103derea temperaturii \u021bintite.<\/li>\n<li><strong>Diferen\u021ba fa\u021b\u0103 de HIFU (Ultrasunete Focalizate de Intensitate \u00cenalt\u0103):<\/strong> IRE nu se bazeaz\u0103 pe mecanisme termice. Acest lucru o face o op\u021biune mai sigur\u0103 \u00een zone \u00een care metodele bazate pe c\u0103ldur\u0103 pot d\u0103una structurilor sensibile.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"Cine_este_candidat_pentru_NanoKnife_in_tratamentul_cancerului_de_prostata\"><\/span>Cine este candidat pentru NanoKnife \u00een tratamentul cancerului de prostat\u0103?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Tratamentul cu NanoKnife este indicat pentru anumite categorii de pacien\u021bi diagnostica\u021bi cu cancer de prostat\u0103. De regul\u0103, este vorba despre b\u0103rba\u021bi cu boal\u0103 localizat\u0103, care doresc s\u0103 evite efectele secundare majore ale procedurilor conven\u021bionale, precum chirurgia sau radioterapia. Tumorile cu risc sc\u0103zut p\u00e2n\u0103 la moderat \u0219i localizate \u00eentr-un singur lob al prostatei r\u0103spund, \u00een general, foarte bine la aceast\u0103 terapie.<\/p>\n<p>\u00cen special, urm\u0103torii pacien\u021bi sunt considera\u021bi candida\u021bi ideali:<\/p>\n<ul>\n<li aria-level=\"1\">Pacien\u021bi cu stadiul clinic \u2264T2c<\/li>\n<li aria-level=\"1\">Scor Gleason 3+4 sau 4+3<\/li>\n<li aria-level=\"1\">Nivel PSA \u226415 ng\/mL<\/li>\n<\/ul>\n<p>Pacien\u021bii care doresc s\u0103 p\u0103streze o calitate ridicat\u0103 a vie\u021bii, mai ales \u00een ceea ce prive\u0219te controlul urinar \u0219i func\u021bia sexual\u0103, pot beneficia semnificativ de NanoKnife. Cei afla\u021bi la v\u00e2rst\u0103 \u00eenaintat\u0103 \u0219i cu alte afec\u021biuni medicale, pentru care chirurgia nu este recomandat\u0103, pot de asemenea fi trata\u021bi cu succes. De asemenea, este o op\u021biune pentru b\u0103rba\u021bii care au fost trata\u021bi anterior prin radioterapie \u0219i la care boala a recidivat, oferind un risc mai sc\u0103zut de complica\u021bii. \u00cen schimb, pacien\u021bii cu metastaze sau un scor Gleason \u22658 au nevoie de tratamente mai agresive, NanoKnife nefiind considerat\u0103 cea mai potrivit\u0103 metod\u0103.<\/p>\n<p><span data-sheets-root=\"1\">\n\t<section class=\"section\" id=\"section_973853662\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n\n<div class=\"row\"  id=\"row-2099113405\">\n\n\n\t<div id=\"col-1859692020\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner box-shadow-2\"  >\n\t\t\t\n\t\t\t\n\n<div class=\"row\"  id=\"row-36385532\">\n\n\n\t<div id=\"col-186318952\" class=\"col whatsapp-alani hide-for-small medium-3 small-12 large-3\"  >\n\t\t\t\t<div class=\"col-inner box-shadow-2\" 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\"ak_js_1\" ).setAttribute( \"value\", ( new Date() ).getTime() );\n<\/script>\n<\/p><div class=\"wpcf7-response-output\" aria-hidden=\"true\"><\/div>\n<\/form>\n<\/div>\n\n\n\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-1068289247 > .col-inner {\n  margin: 0px 0px -60px 0px;\n}\n<\/style>\n\t<\/div>\n\n\t\n\n\t<div id=\"col-1194515869\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\n\t<div id=\"text-1242347479\" class=\"text\">\n\t\t\n\n<p>*V\u0103 recomand\u0103m s\u0103 completa\u021bi toate c\u00e2mpurile pentru a primi cel mai bun r\u0103spuns posibil.<\/p>\n\t\t\n<style>\n#text-1242347479 {\n  font-size: 0.85rem;\n  line-height: 1.5;\n}\n@media (min-width:550px) {\n  #text-1242347479 {\n    line-height: 0.75;\n  }\n}\n<\/style>\n\t<\/div>\n\t\n\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-1194515869 > .col-inner {\n  margin: 0px 0px -40px 0px;\n}\n<\/style>\n\t<\/div>\n\n\t\n\n<\/div>\n\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-291875841 > .col-inner {\n  padding: 0px 0px 0px 0px;\n  margin: 0px 0px -20px 0px;\n}\n@media (min-width:550px) {\n  #col-291875841 > .col-inner {\n    padding: 20px 0px 0px 0px;\n    margin: 0px 0px -66px 0px;\n  }\n}\n<\/style>\n\t<\/div>\n\n\t\n\n<\/div>\n\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-1859692020 > .col-inner {\n  padding: 30px 10px 0px 10px;\n  border-radius: 30px;\n}\n@media (min-width:550px) {\n  #col-1859692020 > .col-inner {\n    padding: 0px 20px 0px 0px;\n  }\n}\n<\/style>\n\t<\/div>\n\n\t\n\n<\/div>\n\n\t\t<\/div>\n\n\t\t\n<style>\n#section_973853662 {\n  padding-top: 30px;\n  padding-bottom: 30px;\n}\n<\/style>\n\t<\/section>\n\t<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Cat_de_eficient_este_NanoKnife_in_tratarea_cancerului_de_prostata\"><\/span>C\u00e2t de eficient este NanoKnife \u00een tratarea cancerului de prostat\u0103?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>NanoKnife se distinge printr-o serie de avantaje notabile, dar comport\u0103 \u0219i anumite riscuri.<\/p>\n<p><strong>Beneficii:<\/strong><\/p>\n<ul>\n<li><strong>Minimizarea efectelor secundare:<\/strong> NanoKnife, fiind un tratament non-termic, protejeaz\u0103 \u021besuturile vecine. Astfel, spre deosebire de chirurgia sau radioterapia tradi\u021bionale, riscul de incontinen\u021b\u0103 \u0219i probleme erectile este redus.<\/li>\n<li><strong>Conservarea func\u021biilor:<\/strong> Tehnica ocrote\u0219te nervii de l\u00e2ng\u0103 prostat\u0103, p\u0103str\u00e2nd func\u021bia urinar\u0103 \u0219i erectil\u0103, un avantaj important \u00een compara\u021bie cu prostatectomia radical\u0103 sau radioterapia.<\/li>\n<li><strong>Recuperare rapid\u0103:<\/strong> Fiind minim invaziv\u0103, permite de obicei externarea \u00een aceea\u0219i zi \u0219i revenirea rapid\u0103 la activit\u0103\u021bile zilnice; utilizarea cateterului este de scurt\u0103 durat\u0103.<\/li>\n<li><strong>\u021aintire precis\u0103:<\/strong> Este potrivit\u0103 pentru zone dificile din prostat\u0103 \u0219i nu afecteaz\u0103 structuri precum sfincterul uretral.<\/li>\n<\/ul>\n<p><strong>Riscuri:<\/strong><\/p>\n<ul>\n<li><strong>Recidiva cancerului:<\/strong> Chiar dac\u0103 terapia ini\u021bial\u0103 se dovede\u0219te eficient\u0103, exist\u0103 un risc de recidiv\u0103. Aproximativ 15-30% dintre pacien\u021bi pot avea nevoie de tratament suplimentar \u00een primii 5 ani, necesit\u00e2nd o monitorizare permanent\u0103.<\/li>\n<li><strong>Statut experimental:<\/strong> Lipsesc date concludente pe termen lung. Prin urmare, tratamentul e recomandat \u00eendeosebi \u00een cazuri bine selectate, \u00een timp ce cercet\u0103rile pentru evaluarea rezultatelor pe termen lung sunt \u00een desf\u0103\u0219urare.<\/li>\n<\/ul>\n<p><span data-sheets-root=\"1\">\n\t<section class=\"section dark\" id=\"section_1940239718\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\r\n\r\n\t<div id=\"gap-1900754055\" class=\"gap-element clearfix hide-for-medium\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1900754055 {\n  padding-top: 10px;\n}\n<\/style>\n\t<\/div>\n\t\r\n\r\n<div class=\"row align-middle\"  id=\"row-1246966554\">\r\n\r\n\n\t<div id=\"col-703175306\" class=\"col medium-8 small-12 large-8\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\r\n\r\n\t<div id=\"text-2631454988\" class=\"text\">\n\t\t\r\n\r\n<div><strong>Contacteaz\u0103-l acum pe Prof. Dr. \u00d6zg\u00fcr K\u0131l\u0131\u00e7kesmez pentru informa\u021bii detaliate \u0219i pentru a programa o consulta\u021bie!<\/strong><\/div>\r\n\t\t\n<style>\n#text-2631454988 {\n  font-size: 1.25rem;\n  text-align: center;\n}\n@media (min-width:550px) {\n  #text-2631454988 {\n    font-size: 1.15rem;\n  }\n}\n@media (min-width:850px) {\n  #text-2631454988 {\n    font-size: 1.5rem;\n    text-align: left;\n  }\n}\n<\/style>\n\t<\/div>\n\t\r\n\r\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-703175306 > .col-inner {\n  padding: 20px 0px 0px 0px;\n  margin: 0px 0px -10px 0px;\n}\n@media (min-width:550px) {\n  #col-703175306 > .col-inner {\n    padding: 0px 0px 0px 0px;\n  }\n}\n<\/style>\n\t<\/div>\n\n\t\r\n\n\t<div id=\"col-1203699081\" class=\"col medium-4 small-12 large-4\"  >\n\t\t\t\t<div class=\"col-inner text-center\"  >\n\t\t\t\n\t\t\t\r\n\r\n<a href=\"https:\/\/api.whatsapp.com\/send\/?phone=905405032303&#038;text=Bun\u0103%2C+v\u0103+contactez+de+pe+https%3A%2F%2Fozgurkilickesmez.com%2F&#038;type=phone_number&#038;app_absent=0\" target=\"_blank\" class=\"button alert is-small box-shadow-5\" rel=\"noopener\" style=\"border-radius:10px;padding:5px 20px 5px 20px;\">\n\t\t<span>Contact prin Whatsapp<\/span>\n\t<i class=\"icon-whatsapp\" aria-hidden=\"true\"><\/i><\/a>\n\r\n\r\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-1203699081 > .col-inner {\n  padding: 20px 0px 0px 0px;\n}\n<\/style>\n\t<\/div>\n\n\t\r\n\r\n<\/div>\r\n\r\n\t\t<\/div>\n\n\t\t\n<style>\n#section_1940239718 {\n  padding-top: 0px;\n  padding-bottom: 0px;\n  background-color: #396cf0;\n}\n<\/style>\n\t<\/section>\n\t\r\n\t<div id=\"gap-2094721244\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-2094721244 {\n  padding-top: 20px;\n}\n<\/style>\n\t<\/div>\n\t\r\n<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Care_este_perspectiva_pe_termen_lung_pentru_pacientii_tratati_cu_NanoKnife\"><\/span>Care este perspectiva pe termen lung pentru pacien\u021bii trata\u021bi cu NanoKnife?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Prognosticul pentru pacien\u021bii cu cancer de prostat\u0103 care au beneficiat de NanoKnife este unul promi\u021b\u0103tor, iar controalele periodice sunt esen\u021biale pentru a men\u021bine succesul terapeutic. Metoda IRE distruge seleciv \u021besutul canceros, conserv\u00e2nd nervii \u0219i \u021besuturile de sus\u021binere din jur, ceea ce reduce riscul de efecte adverse. \u00cen acela\u0219i timp, evalu\u0103rile post-terapie permit depistarea timpurie a eventualelor recidive.<\/p>\n<p>\u00cen timpul monitoriz\u0103rii de dup\u0103 tratament, se urm\u0103resc urm\u0103torii pa\u0219i:<\/p>\n<ul>\n<li><strong>Testul PSA:<\/strong> Se efectueaz\u0103 o dat\u0103 la 3 luni pentru a urm\u0103ri nivelurile de antigen prostatic specific. Cre\u0219terile valorilor pot indica reapari\u021bia bolii.<\/li>\n<li><strong>IRM (MRI):<\/strong> O dat\u0103 la 6 luni, investiga\u021biile RMN multiparametrice pot eviden\u021bia eventualele leziuni suspecte sau reapar\u0103.<\/li>\n<li><strong>Biopsia:<\/strong> Dac\u0103 nivelul PSA cre\u0219te ori dac\u0103 apar modific\u0103ri la RMN, se va efectua o biopsie pentru a confirma dac\u0103 exist\u0103 recidiv\u0103.<\/li>\n<\/ul>\n<p>Din perspectiva eficacit\u0103\u021bii pe termen lung, IRE asigur\u0103 un procent de 90-97% de control al bolii, \u00eens\u0103 se estimeaz\u0103 c\u0103 p\u00e2n\u0103 la 15% dintre pacien\u021bi pot experimenta recidiva. \u00cen astfel de cazuri, se pot alege metode de abla\u021bie focal\u0103 repetate, care s\u0103 controleze boala f\u0103r\u0103 proceduri invazive extinse. Metoda NanoKnife promite s\u0103 reduc\u0103 \u0219ansele de recidiv\u0103 \u0219i s\u0103 ofere rezultate durabile.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>IRE Nanoknife \u00een cancerul de prostat\u0103 este o tehnic\u0103 avansat\u0103 de abla\u021bie care utilizeaz\u0103 impulsuri electrice pentru a distruge celulele tumorale. Procedura se bazeaz\u0103 pe electroporarea ireversibil\u0103, p\u0103str\u00e2nd structurile vasculare \u0219i nervoase adiacente intacte. Tratamentul cu Nanoknife se efectueaz\u0103 sub ghidaj imagistic \u0219i permite distrugerea precis\u0103 a leziunii tumorale. Avantajul metodei const\u0103 \u00een men\u021binerea func\u021bionalit\u0103\u021bii [&#8230;]\n","protected":false},"author":2,"featured_media":9679,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[321],"tags":[],"class_list":["post-9676","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tratamente"],"_links":{"self":[{"href":"https:\/\/ozgurkilickesmez.com\/ro\/wp-json\/wp\/v2\/posts\/9676","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ozgurkilickesmez.com\/ro\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ozgurkilickesmez.com\/ro\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ozgurkilickesmez.com\/ro\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ozgurkilickesmez.com\/ro\/wp-json\/wp\/v2\/comments?post=9676"}],"version-history":[{"count":2,"href":"https:\/\/ozgurkilickesmez.com\/ro\/wp-json\/wp\/v2\/posts\/9676\/revisions"}],"predecessor-version":[{"id":12084,"href":"https:\/\/ozgurkilickesmez.com\/ro\/wp-json\/wp\/v2\/posts\/9676\/revisions\/12084"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ozgurkilickesmez.com\/ro\/wp-json\/wp\/v2\/media\/9679"}],"wp:attachment":[{"href":"https:\/\/ozgurkilickesmez.com\/ro\/wp-json\/wp\/v2\/media?parent=9676"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ozgurkilickesmez.com\/ro\/wp-json\/wp\/v2\/categories?post=9676"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ozgurkilickesmez.com\/ro\/wp-json\/wp\/v2\/tags?post=9676"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}