{"id":10460,"date":"2024-10-09T10:36:39","date_gmt":"2024-10-09T07:36:39","guid":{"rendered":"https:\/\/ozgurkilickesmez.com\/?p=10460"},"modified":"2026-10-13T22:22:02","modified_gmt":"2026-10-13T19:22:02","slug":"ire-nanoknife-in-prostate-cancer","status":"publish","type":"post","link":"https:\/\/ozgurkilickesmez.com\/en\/ire-nanoknife-in-prostate-cancer\/","title":{"rendered":"IRE (NanoKnife) for Prostate Cancer: Procedure, Benefits and Risks"},"content":{"rendered":"

IRE (Irreversible Electroporation) with NanoKnife is a minimally invasive treatment for prostate cancer. It uses electrical pulses to disrupt cancer cell membranes, leading to targeted cell death without heat damage.<\/span><\/p>\n

The technique is performed under ultrasound or MRI guidance, allowing precise treatment of cancerous lesions. Surrounding structures such as nerves and blood vessels are largely preserved, reducing side effects.<\/span><\/p>\n

Compared to surgery or radiation, IRE offers the advantage of maintaining urinary and sexual function. This makes it a valuable option for patients seeking organ-preserving treatment alternatives.<\/span><\/p>\n

IRE NanoKnife is suitable for localized prostate cancer or recurrent disease after conventional therapy. It is repeatable, safe, and effective in carefully selected patients.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Treatment Method<\/td>\nIrreversible Electroporation (IRE) – NanoKnife<\/td>\n<\/tr>\n
Definition<\/td>\nA minimally invasive treatment in prostate cancer that uses high\u2011voltage electrical currents to increase the permeability of cancer cell membranes, causing cell death.<\/td>\n<\/tr>\n
Applications<\/td>\nEarly\u2011stage prostate cancer, small and localized tumors, patients unsuitable for or declining surgery or radiotherapy.<\/td>\n<\/tr>\n
Advantages<\/td>\nEffectively targets the tumor region while causing minimal damage to surrounding nerves, vessels, and tissues; provides an advantage in preserving urinary continence and sexual function.<\/td>\n<\/tr>\n
Procedure<\/td>\nUnder general anesthesia and guided by ultrasound or MRI, thin electrodes are placed into the tumor region; electrical pulses are delivered to cancer cells. The procedure typically lasts 1\u20132 hours.<\/td>\n<\/tr>\n
Side Effects<\/td>\nTemporary pain after the procedure, risk of urinary tract infection, rarely difficulty urinating, tenderness at the treatment site; serious side effects are rare.<\/td>\n<\/tr>\n
Success Rate<\/td>\nHigh success rate in early\u2011stage and localized tumors; varies depending on tumor size and location.<\/td>\n<\/tr>\n
Follow\u2011Up<\/td>\nRegular monitoring of prostate\u2011specific antigen (PSA) levels post\u2011procedure, MRI or biopsy to assess treatment response.<\/td>\n<\/tr>\n
Alternative Methods<\/td>\nRadical prostatectomy, radiotherapy, focal ablation methods (cryotherapy, HIFU).<\/td>\n<\/tr>\n
Related Conditions<\/td>\nProstate cancer, low\u2011 and intermediate\u2011risk localized prostate tumors.<\/td>\n<\/tr>\n
Precautions<\/td>\nPre\u2011procedure antibiotic use is recommended to reduce infection risk; the patient\u2019s PSA and MRI results are considered in planning the procedure.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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